Agent Skill
2/7/2026

nf-to-galaxy

Router skill for Nextflow to Galaxy conversions - directs to appropriate sub-skill

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galaxyproject
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npx skills add galaxyproject/galaxy-skills

SKILL.md

Namenf-to-galaxy
DescriptionRouter skill for Nextflow to Galaxy conversions - directs to appropriate sub-skill

name: nf-to-galaxy description: Router skill for Nextflow to Galaxy conversions - directs to appropriate sub-skill

Nextflow to Galaxy Conversion (Router)

Purpose

This is a router skill that directs you to the appropriate specialized skill based on what you're converting.

For complete pipelines, you are expected to include bioinformatics best-practice sanity checks and discuss QC + reporting requirements (e.g. MultiQC). See nf-pipeline-to-galaxy-workflow/SKILL.md.


What Are You Converting?

Option 1: Single Nextflow Process → Galaxy Tool

Converting: One Nextflow process to one Galaxy tool XML

Example: HYPHY_FEL process → hyphy_fel.xml tool

Use skill: nf-process-to-galaxy-tool

When to use:

  • Creating a Galaxy tool wrapper for a specific bioinformatics tool
  • You've identified a missing tool during pipeline conversion
  • Converting a single nf-core module

Option 2: Nextflow Subworkflow → Galaxy Workflow

Converting: Multiple connected Nextflow processes to a Galaxy workflow

Example: PROCESS_VIRAL_NONRECOMBINANT subworkflow → Galaxy .ga workflow

Use skill: nf-subworkflow-to-galaxy-workflow

When to use:

  • Converting a logical group of processes
  • Building a reusable workflow component
  • Most processes already have Galaxy tools

Option 3: Complete Nextflow Pipeline → Galaxy Solution

Converting: Full Nextflow pipeline to complete Galaxy solution

Example: CAPHEINE pipeline → Multiple Galaxy workflows + any missing tools

Use skill: nf-pipeline-to-galaxy-workflow

When to use:

  • Converting an nf-core pipeline
  • Large-scale conversion project
  • Need to plan tool creation + workflow assembly

Key Concepts

Before using any sub-skill, understand these mappings:

AspectNextflowGalaxy
Unit of workProcess (Groovy DSL)Tool (XML)
OrganizationModule (directory)Tool directory
Workflow format.nf files (code).ga files (JSON)
DependenciesContainers or CondaConda via <requirements>
Inputs/OutputsChannelsDatasets with datatypes

Critical: One Nextflow process = One Galaxy tool

Read: nextflow-galaxy-terminology.md for detailed conceptual mapping


Getting Started

New to this skill? See README.md for file organization and navigation.

Using Galaxy integration? See ../../galaxy-integration/README.md and ../../galaxy-integration/galaxy-integration.md.


Shared Resources

Core Guides

  • ../../galaxy-integration/galaxy-integration.md - Galaxy MCP/BioBlend: setup, tool checking, workflow testing
  • check-tool-availability.md - Manual tool checking across repositories
  • testing-and-validation.md - Routing page to canonical testing docs
  • ../../tool-dev/references/testing.md - Tool testing with Planemo

Tool Discovery Order (Installed vs Available vs Missing)

Before you conclude a tool is "missing", distinguish:

  1. Installed on your target Galaxy instance (ready to use in a .ga).
  2. Not installed, but has an existing wrapper that can be installed (ToolShed / tools-iuc / known maintainers).
  3. No wrapper exists (tool wrapper must be created).

If you determine (3) applies, use nf-process-to-galaxy-tool/ to create a Galaxy tool wrapper.

When a tool is not installed on the target instance, follow the repository search order in check-tool-availability.md.

Common ToolShed owners to check (not exhaustive):

  • iuc
  • devteam
  • bgruening
  • genouest

Reference Documentation

  • nextflow-galaxy-terminology.md - Concept mappings (process→tool, workflow→.ga)
  • process-to-tool.md - Process → Tool conversion details
  • workflow-to-ga.md - Workflow → .ga conversion details
  • container-mapping.md - Container → Conda package mapping
  • datatype-mapping.md - File patterns → Galaxy datatypes
  • tool-sources.md - Where to create tools (tools-iuc vs custom)

Scripts & Examples

  • scripts/ - Automation scripts (see scripts/README.md)
  • examples/ - Complete conversion examples (see examples/README.md)

Quick Decision Tree

What are you converting?
│
├─ Single process?
│  └─ Use: nf-process-to-galaxy-tool
│
├─ Subworkflow (multiple processes)?
│  └─ Use: nf-subworkflow-to-galaxy-workflow
│
└─ Complete pipeline?
   └─ Use: nf-pipeline-to-galaxy-workflow

Sub-Skills

nf-process-to-galaxy-tool/

Convert a single Nextflow process to a Galaxy tool XML.

nf-subworkflow-to-galaxy-workflow/

Convert a Nextflow subworkflow to a Galaxy workflow.

nf-pipeline-to-galaxy-workflow/

Convert a complete Nextflow pipeline to a Galaxy solution.

Skills Info
Original Name:nf-to-galaxyAuthor:galaxyproject